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Associate Professor Jon Whitehead

Associate Professor Jon Whitehead

After completing his PhD at the University of Liverpool (UK) in 1994, Dr Whitehead moved to the University of Cambridge (UK) where he began work in the area of insulin signalling, insulin resistance and obesity. In 1999 he secured an International Travelling Fellowship from the Wellcome Trust, taking up a position at the Institute for Molecular Bioscience at The University of Queensland (UQ), then the Diabetes & Obesity Research Program at the Garvan Institute of Medical Research in Sydney. In 2002 he returned to UQ to take up an independent position as a Lions Senior Medical Research Fellow. In 2008 he was awarded an NHMRC Senior Research Fellowship and relocated to Mater Research in early 2010 where he heads the Metabolic Medicine Team and the Understanding and Preventing Disease Theme.

Recent publications

  • Keshvari S., F. Rose, H. Charlton, N. Scheiber, J. Webster, YH. Kim, C. Ng, R. Parton, J. Whitehead.  Characterisation of the Adiponectin Receptors: The non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface.  Biochem Biophys Res Comm 432: 28-33, 2013
  • Hughes T., D. Kim, J. Marjason, J. Proeitto, J. Whitehead, J. Vath. Multiple Ascending Dose Controlled Trial of Beloranib, a Novel Obesity Treatment for Safety, Tolerability and Weight Loss in Obese Women.  Int J Obesity (In press) 2013
  • Phillips L., J. Peake, X. Zhang, I. Hickman, D. Briskey, B. Huang, P. Simpson, S. Li, J. Whitehead, J. Martin, J. Prins.  Postprandial total and HMW adiponectin following a high-fat meal in lean, obese and diabetic men.  Eur J Clinical Nutrition 67: 377-84, 2013
  • Wright O., I. Hickman, W. Petchey, C. Sullivan, C. Ong, F. Rose, C. Ng, J. Prins, J. Whitehead, T. O’Moore-Sullivan.  The effect of 25-hydroxyvitmain D on insulin sensitivity in obesity: is it mediated by adiponectin?  Can J Phys & Pharmacol (In press) 2013
  • Thomas E., J. Gunter, J. Webster, N. Schieber, V. Oorschot, R. Parton, J. Whitehead.  Different Characteristics and Nucleotide Binding Properties of Inosine Monophosphate Dehydrogenase (IMPDH) Isoforms.  PLoS One 7: e51096, 2012
  • Luo X., L. Hutley, J. Webster, YH. Kim, DF Liu, F. Newell, C. Widberg, A. Bachmann, N. Turner, C. Schmitz-Peifer, J. Prins, GS Yang, J. Whitehead. Identification of BMP and Activin Membrane Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors.  Diabetes 61: 124-36, 2012
  • Hutley L., F. Newell, C. Widberg, Y-H. Kim, X. Luo, W. Shurety, J. Prins, J. Whitehead. A putative role for endogenous FGF-2 in FGF-1 mediated differentiation of human preadipocytes.  Mol Cell Endo 339: 165-71, 2011
  • Whitehead J. New conductors for the peroxisome proliferator-activated receptor  (PPAR) orchestra. Int J Biochem  Cell Biol 43: 1071-74, 2011
  • Rose. F., J. Webster, J. Barry, L. Phillips, A. Richards, J. Whitehead.  Synergistic effects of ascorbic acid and thiazolidinedione on secretion of high molecular weight adiponectin from human adipocytes. Diabetes Obes Metab 12: 1084-9, 2010
  • Simpson. F., J. Whitehead.  Adiponectin – it’s all about the modifications.  Int J Biochem Cell Biol 42, 1716-1728, 2010
  • Charlton. H., J. Webster, S. Kruger, F. Simpson, A. Richards, J. Whitehead.  ERp46 binds to AdipoR1, but not AdipoR2, and modulates adiponectin signalling.  Biochem Biophys Res Comm 392, 239-4, 2010
  • Richards. A., M. Colgrave, Z. Jialiang, J. Webster, F. Simpson, E. Preston, D. Wilks, K. Hoehn, M. Stephenson, G. Macdonald, J. Prins, G. Cooney, A. Xu, J. Whitehead.  Sialic acid modification of adiponectin is not required for multimerization or secretion but determines half-life in circulation.  Mol Endo 24, 229-39, 2010

     

 

 

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